NEWS 2018-02-16T16:58:53+00:00


New Publication – “Integrative structure and functional anatomy of a nuclear pore complex”

Illuminating the Gateway to the Nucleus

Read our latest publication in Nature titled: Integrative structure and functional anatomy of a nuclear pore complex.

A tremendous feat of structural, molecular, chemical and cellular biology, our NCDIR researchers and collaborators encompassing 10 different institutions across the USA have illuminated the engineering feat of the cell when creating the largest protein complex in the cell, the Nuclear Pore Complex.

This biological blueprint describes the positioning of the 552 proteins that form the complex, relating the structural formation to that of a suspension bridge, made up of both structured and flexible components that enables the complex to withstand mammoth amounts of stress.

Dissecting the Nuclear pore complex involved every lab in the NCDIR not to mention numerous collaborators spanning the USA. Collaboration is at the heart of great science.

Access the publication on the Nature site or here!

March 14th, 2018|

NCDIR clone database

Coming soon.

Our clone database is access to a repository of all the clones generated by NCDIR labs. This page is currently under construction, but will be a platform to request a clone from the NCDIR to benefit your research.

March 4th, 2018|

The NCDIR is in the News!

John LaCava, of the Rout Lab, was recently profiled and featured on talking about raising åantibodies against protein complexes! Read the full article on!

Dr. John LaCava of Rockefeller

November 9th, 2017|

Summer Teaching in Barcelona by our NCDIR members!

Dr. John LaCava and Dr. Natalia Ketaren from the Rout Lab were invited to teach a research program at The School of Molecular and Theoretical Biology held in Barcelona, Spain. The Zimin Foundation funded school is under the helm of HHMI investigator Dr. Fyodor Kondrashov, and teaches late high-school students and early undergraduates various scientific research projects, each mentored by world –renowned scientists, over a course of 2 weeks.

Students get hands-on experience of what it is like to conceive, develop and carry-out hypothesis driven scientific research, performing either computational driven work or benchwork, culminating in a conference showcasing the novel findings of each labs research project. This is the 2nd year in a row that Dr. LaCava with the help of Dr. Ketaren carried out a research course for the school.

The School of molecular and theoretical biology, Class of 2017, Barcelona, Spain.

To read more about the School of Molecular and Theoretical Biology and the projects carried out by Dr. LaCava and Dr. Ketaren at the school see below!

August 2nd, 2017|