2015 Publications

  1. Aitchison JD, Rout MP. “The interactome challenge.” J Cell Biol. 2015 Nov 23;211(4):729-32. doi: 10.1083/jcb.201510108. Epub 2015 Nov 16. PMC4657177
  2. Carter L, Kim SJ, Schneidman-Duhovny D, Stöhr J, Poncet-Montange G, Weiss TM, Tsuruta H, Prusiner SB, Sali A. “Prion Protein-Antibody Complexes Characterized by Chromatography-Coupled Small-Angle X-Ray Scattering.” Biophys J. 2015 Aug 18;109(4):793-805. doi: 10.1016/j.bpj.2015.06.065. PMC4547163
  3. Danziger SA, Reiss DJ, Ratushny AV, Smith JJ, Plaisier CL, Aitchison JD, Baliga NS. “Bicluster Sampled Coherence Metric (BSCM) provides an accurate environmental context for phenotype predictions.” BMC Syst Biol. 2015;9 Suppl 2:S1. doi: 10.1186/1752-0509-9-S2-S1. Epub 2015 Apr 15. PMC4407105
  4. Dokudovskaya S, Rout MP. “SEA you later alli-GATOR - a dynamic regulator of the TORC1 stress response pathway.” J Cell Sci. 2015 Jun 15;128(12):2219-2228. Epub 2015 May 1. Review. PMC4487016
  5. Fridy PC, Thompson MK, Ketaren NE, Rout MP. “Engineered high-affinity nanobodies recognizing staphylococcal Protein A and suitable for native isolation of protein complexes.” Anal Biochem. 2015 May 15;477:92-4. doi: 10.1016/j.ab.2015.02.013. Epub 2015 Feb 21. PMC4487016
  6. Hakhverdyan Z, Domanski M. Hough L, Oroskar AA, Oroskar AR, Keegan S, Dilworth DJ, Molloy K, Sherman V, Aitchison JD, Fenyö D, Chait BT, Jensen TH, Rout MP and LaCava J. “Rapid, Optimized Interactomic Screening.” Nat Methods. 2015 Jun;12(6):553-60. doi: 10.1038/nmeth.3395 PMC4449307
  7. Heider MR, Gu M, Duffy CM, Mirza AM, Marcotte LL, Walls AC, Farrall N, Hakhverdyan Z, Field MC, Rout MP, Frost A, Munson M. “Subunit connectivity, assembly determinants and architecture of the yeast exocyst complex.” Nat Struct Mol Biol. 2016 Jan;23(1):59-66. doi: 10.1038/nsmb.3146. Epub 2015 Dec 14. PMC4752824
  8. Hough LE, Dutta K, Sparks S, Temel DB, Kamal A, Tetenbaum-Novatt J, Rout MP, Cowburn D. “The molecular mechanism of nuclear transport revealed by atomic-scale measurements.” Elife. 2015 Sep 15;4. pii: e10027. doi: 10.7554/eLife.10027. PMC4621360
  9. Hubin EA, Tabib-Salazar A, Humphrey LJ, Flack JE, Olinares PD, Darst SA, Campbell EA, Paget MS. “Structural, functional, and genetic analyses of the actinobacterial transcription factor RbpA.” Proc Natl Acad Sci U S A. 2015 Jun 9;112(23):7171-6. doi: 10.1073/pnas.1504942112. Epub 2015 May 26. PMC4466734
  10. Kleiner RE, Verma P, Molloy KR, Chait BT, Kapoor TM. “Chemical proteomics reveals a γH2AX-53BP1 interaction in the DNA damage response.” Nat Chem Biol. 2015 Sep 7. doi: 10.1038/nchembio.1908. [Epub ahead of print] PMC4589150
  11. Krutchinsky AN, Padovan JC, Cohen H, Chait BT. “Optimizing electrospray interfaces using slowly diverging conical duct (ConDuct) electrodes.” J Am Soc Mass Spectrom. 2015 Apr;26(4):659-67. doi: 10.1007/s13361-014-1063-0. Epub 2015 Feb 10. PMC4361383
  12. Krutchinsky AN, Padovan JC, Cohen H, Chait BT. “Maximizing Ion Transmission from Atmospheric Pressure into the Vacuum of Mass Spectrometers with a Novel Electrospray Interface.” J Am Soc Mass Spectrom. 2015 Apr;26(4):649-58. doi: 10.1007/s13361-014-1062-1. Epub 2015 Jan 15. PMC4361285
  13. LaCava J, Molloy KR, Taylor MS, Domanski M, Chait BT, Rout MP. “Affinity proteomics to study endogenous protein complexes: pointers, pitfalls, preferences and perspectives.” Biotechniques. 2015 Mar 1;58(3):103-19. doi: 10.2144/000114262. eCollection 2015 Mar. PMC4465938
  14. Lord CL, Timney BL, Rout MP, Wente SR. “Altering nuclear pore complex function impacts longevity and mitochondrial function in S. cerevisiae.” J Cell Biol. 2015 Mar 16;208(6):729-44. doi: 10.1083/jcb.201412024. PMC4362458
  15. Luo J, Cimermancic P, Viswanath S, Ebmeier CC, Kim B, Dehecq M, Raman V, Greenberg CH, Pellarin R, Sali A, Taatjes DJ, Hahn S, Ranish J. “Architecture of the Human and Yeast General Transcription and DNA Repair Factor TFIIH.” Mol Cell. 2015 Sep 3;59(5):794-806. doi: 10.1016/j.molcel.2015.07.016. PMC4560838
  16. Morris DH, Yip CK, Shi Y, Chait BT, Wang QJ. “Beclin 1-VPS34 Complex Architecture: Understanding the Nuts and Bolts of Therapeutic Targets.” Front Biol (Beijing). 2015 Oct;10(5):398-426. Epub 2015 Nov 4. PMC4682202
  17. Robinson PJ, Trnka MJ, Pellarin R, Greenberg CH, Bushnell DA, Davis R, Burlingame AL, Sali A, Kornberg RD. “Molecular architecture of the yeast Mediator complex.” Elife. 2015 Sep 24;4. pii: e08719. doi: 10.7554/eLife.08719. PMC4631838
  18. Shi Y, Pellarin R, Fridy PC, Fernandez-Martinez J, Thompson MK, Li Y, Wang QJ, Sali A, Rout MP, Chait BT. “A strategy for dissecting the architectures of native macromolecular assemblies.” Nat Methods. 2015 Dec;12(12):1135-8. doi: 10.1038/nmeth.3617. Epub 2015 Oct 5. PMC4803312
  19. Sun J, Shi Y, Georgescu RE, Yuan Z, Chait BT, Li H, O'Donnell ME. "The architecture of a eukaryotic replisome." Nat Struct Mol Biol. 2015 Dec;22(12):976-82. doi: 10.1038/nsmb.3113. Epub 2015 Nov 2. PMID: 26524492