The National Center for Dynamic Interactome Research (NCDIR) is a Biotechnology Resource Center funded by the NIH. The institute was borne from the desire to create and better available technologies, to enable them to decipher the cellular interactome and its complex dynamics.

NCDIR key principal investigators: Top (left) Andrej Sali, (right) Brian Chait; Bottom (left) John Aitchison, (right) Michael Rout.

At its heart, the NCDIR is made from labs spanning the USA: On the east coast, are Prof. Michael Rout and Prof. Brian Chait at the Rockefeller University; on the west coast, at UCSF, is the lab of Prof. Andrej Sali; and in Seattle Prof. John Aitchison, Co-Director of the Center for Global Infectious Disease Research at Seattle Children’s. These four labs form a core collaboration resulting in numerous methodological advancements in the fields of molecular and cellular biology as well as key insights into how various macromolecular assemblies function in health and disease. The NCDIR has helped many groups implement these methods to advance their research when studying numerous biological processes. (See Collaborate & Training).

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