Our Center’s reagents, methods, and software require substantial infrastructure for their development, including instrumentation, computer hardware, and personnel. Much of the value and impact of the Center depends on the use of our methods and tools by the wider community of biomedical researchers. Therefore, it is a main objective of the Center to provide the infrastructure for facile, timely, and productive use of the NCDIR resources by a broad range of researchers. Beyond on-site training, our website is our most important route for disseminating our discoveries to the biomedical community.

Integrative Modeling Platform (IMP)

The Integrative Modeling Platform (IMP) allows comprehensive structural characterization of biomolecules ranging from small molecules to massive macromolecular complexes. IMP provides an open source C++ and Python toolbox for solving complex modeling problems, and a number of applications for tackling some common problems in a user-friendly way. To learn more about IMP, click here!


The NCDIR is actively optimizing the pipeline for the production of nanobodies, highly interesting naturally occurring antibody variants isolated from Camelids. These 15 kDa antibody fragments are the  topic  of  intense research as a tool for basic and clinical research, diagnostics, and therapeutics. To learn more about nanobodies, click here!

Clone database

The clone database was developed to house all the clones and strains used in the development of the NCDIR’s TR&D, DBP and collaboration and service projects. Many of these clones and strains are available to you upon request. To access the clone database and more information click here!

CX-Circos is the main website providing CX-Circos, a web-based tool for visualization and analysis of chemical crosslinking data, being continuously updated for new features.

CX-Circos version 2 uses new web technologies to migrate most of the computation to user’s browser, enabling responsive visualization in real-time.


The ODELAY/ODELAM platform enables rapid quantitative measurements of growth kinetics in as few as 30 h under a variety of environmental conditions. The software package, provided in python and Matlab, enables the acquisition and analysis of timelapse microscopy for tracking the growth of upwards of hundreds of thousands of individual cells as they grow into microcolonies. This high-resolution analysis enables quantitative and normalized comparisons of growth kinetic parameters both within and between different strains and/or treatments of microcolony forming organisms such as yeast and Mycobacterium tuberculosis. The program can be accessed here:


This software, developed by Max Neal in John Aitchison’s Lab (NCDIR), allows users to functionally profile genes in S. cerevisiae, thereby illuminating their cellular roles. is an external site intended as a resource for scientists to assist with the curation of images of SDS-PAGE protein gels displaying protein co-purification banding patterns resulting from affinity capture experiments. To learn more about, click here!