Funded by a grant from the National Institutes of General Medical Sciences of the National Institute of Health

Welcome to NCDIR!

The National Center for Dynamic Interactome Research (NCDIR) is a Biotechnology Resource Center funded by the NIH. We are four labs across the USA carrying out cutting-edge research in the fields of molecular and cellular biology. We are at the forefront of methodological and technology development to aid researches in both the medical and general sciences. Welcome and explore!



August 16th, 2020 – Research Spotlight!

New Publication!

NCDIR scientists propose new strategies to develop antiviral therapeutics.
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January 30th, 2020 – Research Spotlight!

New Publication!

More info and full text here!

January 13th 2020 – Research Spotlight! 

New Publication!

More info and full text here!

Upcoming Event: NYC RNA Society, April 1st 2019.

The upcoming RNA society Salon will be hosted at The Rockefeller University on April 1st 2019. For more details click here…

March 12th, 2019

New Publication!

For more info and full text, click here!

September 21st, 2018

NCDIR scientists and technology have been featured in a recent publication exploring RNA pol II repression.
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Intergrative Modeling Platform

The Integrative Modeling Platform (IMP) allows comprehensive structural characterization of biomolecules ranging from small molecules to massive macromolecular complexes. IMP provides an open source C++ and Python toolbox for solving complex modeling problems, and a number of applications for tackling some common problems in a user-friendly way.


The NCDIR is actively optimizing the pipeline for the production of nanobodies, highly interesting naturally occurring antibody variants isolated from Camelids. These 15 kDa antibody fragments are the  topic  of  intense research as a tool for basic and clinical research, diagnostics, and therapeutics. is an external site intended as a resource for scientists to assist with the curation of images of SDS-PAGE protein gels displaying protein co-purification banding patterns resulting from affinity capture experiments.